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How Cells reacts to the external stimuli?
Our main research focus is to understand how cells react to the various stimuli. Understanding the cellular signaling network in stem cells and cancer cells is important to identify the molecular targets for putative drugs. In particular, we are studying human pluripotent stem cells to uncover the signaling network of pluripotency maintenance. Using emerging gene editing techniques, we also establish disease model cells from human embryonic stem cells. In other hands, we also study the cellular signaling to control metastasis as well as drug resistance. Bioinformatic tools are applied to predict the putative drugs or key regulators.
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