

Members

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Embryonic stem cells, induced pluripotent stem cells
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Naive and Primed Pluripotency
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Artificial embryo, Blastoid

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Disease modeling for genetic disorder research
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In vivo gene/cell therapy
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Distinctive characteristic of ferroptosis in stem cells

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Molecular mechanism of liver regeneration
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Epigenetic regulation upon cellular dedifferentiation
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Development of regenerative medicine

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Disease modeling and drug discovery by using gene editing tools with PSCs.
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Finding a new therapeutic strategy for genetic disease.
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DNA damage repair and Cas9 gene editing

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Embryonic stem cells, induced pluripotent stem cells
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Naive and Primed Pluripotency
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Artificial embryo, Blastoid

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Epigenetic regulation during early embryogenesis
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First lineage specification
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Embryology
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Developmental biology

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In Vivo Partial Reprogramming for Melanocyte Lineage Regeneration
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Precise Genome Editing for Therapeutic Induction of Beneficial Mutations

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Cell and gene therapy
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Disease modeling

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Dissecting cell-cycle regulation and lineage specification during development using stem cell–based models

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Mechanisms of Liver Reprogramming in Metabolic Dysfunction‑Associated Steatohepatitis (MASH)
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In Vivo Tumor Microenvironment Modeling Using Stem Cell–Derived Teratomas

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In vivo reprogramming in stomach and molecular mechanism of gastric regeneration
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Intestinal aging and regenerative therapy

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In vivo reprogramming in bone marrow and HSCs
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Blood epigenetic clock reversal by hematopoietic reprogramming

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Exploring the world of science...

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Disease in a dish modeling
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Gene-edited disease modeling

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Site-specific large gene insertion
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Gene editing tool development
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RNA editing

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3D disease modeling
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AI-driven gene therapy