YAP1/TAZ/TEAD signaling in PSCs

Genetic alterations and Heterogeneity of PSCs, Ferroptosis regulation in PSCs

Precise genome editing in PSCs

In vivo reprogramming in small intestine

Disease modeling and gene editing

Stem cell Ageing in small intestine

Cell signaling in chemoresistance of cancer cell and pathogenicity of ‘Disease-in-a-Dish’ from human PSCs

Leveraging Data-Driven Approaches for Predicting Drug Mode of Action (MOA) and in vitro Validation

Prediction of phenotype signatures from public database​

Disease modeling for genetic disorder research

In vivo gene/cell therapy

Distinctive characteristic of ferroptosis in stem cells

Molecular mechanism of liver regeneration

Epigenetic regulation upon cellular dedifferentiation

Development of regenerative medicine

Disease modeling and drug discovery by using gene editing tools with PSCs.

Finding a new therapeutic strategy for genetic disease.

DNA damage repair and Cas9 gene editing

Epigenetic regulation in totipotent/ PSCs

Distinct Iron Metabolism in PSCs

Epigenetic regulation during early embryogenesis

First lineage specification
Embryology and totipotent/pluripotent stem cell

Reprogramming mechanisms in hepatic disease conditions

Signaling pathway in intestinal stem cells

Regeneration of Melanocyte Lineage via In Vivo Partial Reprogramming in Radiation-Induced Premature Hair Graying

Genome Editing-Based Disease-in-a-Dish Models to Reveal Mechanisms of Rare Genetic Disorders

​Cell and gene therapy

Disease modeling

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Mechanisms of Liver Reprogramming in Metabolic Dysfunction‑Associated Steatohepatitis (MASH)

In Vivo Tumor Microenvironment Modeling Using Stem Cell–Derived Teratomas

 In vivo reprogramming in stomach and molecular mechanism of gastric regeneration

Disease modeling and gene therapy

In vivo reprogramming in bone marrow and HSCs

Immune modulation during partial reprogramming